David S Younger, MD, MPH, MS, is Adjunct Clinical Associate Professor of Global Public Health at New York University. He serves is Clinical Associate Professor of Neurology at the New York University School of Medicine in the Divisions of Neuromuscular Disease and Neuro-Epidemiology. Dr. Younger has appointments at Lenox Hill Hospital a member of Northwell Health and White Plains Hospital in New York where he is Attending Physician in Neurology.
Dr. Younger is a world-renowned expert in neurology and a highly-trained authority in public health and the author of several books, and over 200 peer-reviewed articles, book chapters, and abstracts. His national ratings on internet blogs attests to his calm deliberate and assiduous detail to the health and concern of his colleagues and patients.
For the past three decades, his work has centered on Neuro-Immunology and more recently, elucidating the importance of the human microbiome to health and disease. Beyond improved microbial cataloguing through high-throughput genetic sequencing, scientists have learned that human beings are superorganisms integrating the identity, function and immunity of resident bacterial, while prepared throughout own innate and adaptive immune systems, to deal with invading organisms. In keeping with the dynamic relation of infection, immunity and inflammation contained in the concept of I-Cubed (I3), neurological illnesses of varied types can arise when protective immunity becomes the source of autoimmunity, conditioned by environmental and genetic factors. This paradigm explains the etiopathogenesis of diverse medical (type 1 diabetes, spondyloarthropathy), neurologic (Lyme neuroborreliosis), and neuropsychiatric disorders (PANDAS, and autism spectrum disorders).
His Master thesis in Epidemiology and subsequent publications emanating from it this year (2016) elucidated the complex understanding of factors conditioning pediatric autoimmune neuropsychiatric disorder associated with group A beta hemolytic strep infection termed PANDAS. (Another article about PANDAS) It is his strong belief that health officials will be called upon to guide the public’s understanding and mitigate the risk of disorders that result from the interplay of the human microbiome and I-Cubed. By focusing his recent research on issues related to the understanding of childhood and adult neuropsychiatric illness especially as concerns the influence of infectious and autoimmune triggers, he has been able to develop programs centered on the influence of immune modulatory therapy. One particular research program in the area of Lyme neuroborreliosis is available on-line for researchers and patients.
His textbook Motor Disorders is presently in its 3rd edition released in 2013 in hard cover and the first edition of Motor Disorders ebook available in one volume or by the chapter released in 2015 have become standard textbooks for medical trainees at New York University and Columbia University. Two other books, Human Lyme Neuroborreliosis and two volume set The Vasculitides (volume 1 and 2) both published in 2015, have been embraced by the medical community and patients alike for its relevance to domestic and global public health. A forthcoming book entitled, Public Health, Neuro-Epidemiology and Health Systems, edited by Dr. Younger offers a comprehensive analysis of the topics for public health trainees, scholars, and practitioners.
At the onset of David's career as a medical scientific researcher and clinician, he was lead investigator in early trials of muscular dystrophy, motor neuron disease, neurolymphomatosis, and vasculitis. More recently, he returned to New York University to accomplish a Master of Public Health (MPH) in Global and Community Health followed by a Master of Science (MS) degree in Epidemiology at Columbia’s Mailman School of Public Health where he graduated in June 2016. He hopes to attend the City University of New York (CUNY) program for the Doctoral Degree of Public Health (Dr.PH) in the Fall 2017.
David holds Editorial Board memberships in various medical scientific journals and serve on the Board of Directors of the National Cooley’s Anemia Foundation.