Section on Implementing Evidence-Based Interventions for Sickle Cell Disease (ISCD)

Sickle cell disease (SCD), an inherited blood disease characterized by anemia, severe pain and other vasoocclusive complications, and early mortality, is endemic to populations residing in sub-Saharan Africa, yet evidence-based interventions are rarely available, accessible or widely adopted for disease management.

The mission of the section for SCD at the ISEE lab is to understand the who, why, where and how interventions for SCD management are adopted by certain communities and not others, and ultimately implement sustainable and scalable evidence-based interventions in a context appropriate manner. Because context matters, approaching interventions with cultural sensitivity and innovation for diverse populations in low resource settings, and continuous engagement of key stakeholders is key to improving health and overall health outcomes. Currently, we are examining the evidence in the existing published literature for sickle cell disease management strategies in low-and middle-income countries. Findings will inform the most effective evidence-based interventions and suitable implementation strategies for SCD management in low-resource settings.

Our Work: 

1. Collaborate with investigators in the Sickle Pan-African Research Consortium (SPARCo) to develop EBI to address SCD
2. Develop an evidence-based protocol to assess implementation outcomes of EBI for SCD in LMICs
3. Assess the scalability of EBI for SCD management in LMICs

Section Leader: Joyce Gyamfi, EdD, MS