Siyu Heng
Siyu Heng
Assistant Professor of Biostatistics
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Professional overview
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Siyu Heng, PhD is an Assistant Professor in the Department of Biostatistics, with an interest in both methodology research and applied research. His areas of expertise are in causal inference, health data science, observational studies, randomized trials, sensitivity analysis, instrumental variables, measurement error, and in survey data and their applications in public health.
Dr. Heng’s research has been published in the Journal of the Royal Statistical Society and in Physical Review, among others. He has been recognized with several awards, including the IPUMS Global Health Research Award for the Best Student Paper; the Lawrence D. Brown Best Paper Award; the ASA Mental Health Statistics Section Student Paper Award; the ENAR Distinguished Student Paper Award; the NESS Student Research Award, and the Wellcome Trust Data Reuse Prize.
Dr. Heng received his PhD in applied mathematics and computational science from the University of Pennsylvania, and his BA in statistics from Nanjing University.
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Education
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PhD Candidate, Applied Mathematics and Computational Science (Statistics Track) University of PennsylvaniaBS, Mathematics, Nanjing University
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Honors and awards
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IPUMS Global Health Research Award for the Best Student Paper, Integrated Public Use Microdata Series (2021)IMS Hannan Graduate Student Travel Award, Institute of Mathematical Statistics (2021)ASA Mental Health Statistics Section Student Paper Award, American Statistical Association Section on Mental Health Statistics (2021)ENAR Distinguished Student Paper Award, International Biometric Society Eastern North American Region (2021)Wellcome Trust Data Reuse Prize: Malaria, Wellcome Trust (2019)Benjamin Franklin Fellowship, University of Pennsylvania School of Arts and Sciences (201620172018)
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Areas of research and study
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Causal InferenceEpidemiologyGlobal HealthHealth EquityInstrumental VariablesObservational StudiesPublic Health PolicyRandomized ExperimentationSocial Sciences
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Publications
Publications
Bias mitigation in matched observational studies with continuous treatments: calipered non-bipartite matching and bias-corrected estimation and inference
AbstractHeng, S., Frazier, A., Heng, S., & Zhou, W. (n.d.).Publication year
2026Journal title
BiometricsVolume
82Issue
1Page(s)
ujag022Abstract~Peri-Rolandic and Occipital Sparing Cortical Edema: A Prevalent MRI Finding in Pediatric Patients with Cerebral Malaria
AbstractHeng, S., Vidal, L., Zandifar, A., Kim, J., Tierradentro-Garc’ia, L. O., Heng, S., Meneses, M., Small, D., Chetcuti, K., O’Brien, N., Postels, D., & others. (n.d.).Publication year
2026Journal title
American Journal of NeuroradiologyVolume
47Issue
2Page(s)
473--481Abstract~Propensity Score Propagation: A General Framework for Design-Based Inference with Unknown Propensity Scores
AbstractHeng, S., Heng, S., Shen, Y., & Guo, Z. (n.d.).Publication year
2026Journal title
arXiv preprint arXiv:2601.13150Abstract~Selecting optimized behavioral interventions from an optimization randomized controlled trial on increasing COVID-19 testing for African American/Black and Latino frontline essential workers not up-to-date on COVID-19 vaccination
AbstractHeng, S., Heng, S., Ye, X., Strayhorn, J. C., Cleland, C. M., Parameswaran, L., & Gwadz, M. (n.d.).Publication year
2026Journal title
Annals of Behavioral MedicineVolume
60Issue
1Page(s)
kaag005Abstract~A Non-Bipartite Matching Framework for Difference-in-Differences with General Treatment Types
AbstractHeng, S., Heng, S., Huang, Y., & Kang, H. (n.d.).Publication year
2025Journal title
arXiv preprint arXiv:2511.21973Abstract~A Universal Framework for Factorial Matched Observational Studies with General Treatment Types: Design, Analysis, and Applications
AbstractHeng, S., Zhu, J., Zhang, T., Silver, D., Matthay, E., El-Shahawy, O., Kang, H., & Heng, S. (n.d.).Publication year
2025Journal title
arXiv preprint arXiv:2512.18997Abstract~Adaptive Dwell Scheduling Based on Q-Learning for Multifunctional Radar System
AbstractHeng, S., Heng, S., Cheng, T., He, Z., Wang, Y., & Liu, L. (n.d.).Publication year
2025Journal title
Journal of Systems Engineering and ElectronicsVolume
36Issue
4Page(s)
985--993Abstract~Bridging the gap between design and analysis: randomization inference and sensitivity analysis for matched observational studies with treatment doses
AbstractHeng, S., Zhang, J., & Heng, S. (n.d.).Publication year
2025Journal title
BiometricsVolume
81Issue
4Page(s)
ujaf156Abstract~Comparing the Treatment and Side Effects of Existing Bariatric Surgery Procedures: An Observational Study
AbstractHeng, S., Yin, Q., Zhang, J., & Heng, S. (n.d.).Publication year
2025Journal title
medRxivPage(s)
2025--12Abstract~Design-Based Causal Inference with Missing Outcomes: Missingness Mechanisms, Imputation-Assisted Randomization Tests, and Covariate Adjustment
AbstractHeng, S., Heng, S., Zhang, J., & Feng, Y. (n.d.).Publication year
2025Journal title
Journal of the American Statistical AssociationPage(s)
1--24Abstract~Determining vaccine responders in the presence of baseline immunity using single-cell assays and paired control samples
AbstractHeng, S., Chen, Z., Heng, S., Tapley, A., De, R. S., & Zhang, B. o. (n.d.).Publication year
2025Journal title
BiostatisticsVolume
26Issue
1Page(s)
kxaf045Abstract~Effects of behavioral intervention components to increase COVID-19 testing for African American/Black and Latine frontline essential workers not up-to-date on COVID-19 vaccination: Results of an optimization randomized controlled trial
AbstractHeng, S., Gwadz, M., Heng, S., Cleland, C. M., Strayhorn, J., Robinson, J. A., Serrano, F., Wang, P., Parameswaran, L., & Chero, R. (n.d.).Publication year
2025Journal title
Journal of Behavioral MedicineVolume
48Issue
4Page(s)
553--571Abstract~Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV
AbstractHeng, S., Mkhize, N. N., Zhang, B. o., Brackett, C., Elyanu, P. J., Tapley, A., Dadabhai, S., Hu, J., Do, B. T., Schuster, D. J., Heptinstall, J., & others. (n.d.).Publication year
2025Journal title
Nature communicationsVolume
16Issue
1Page(s)
8876Abstract~Parent-daughter agreement about HPV vaccination status in Kenya and Malawi
AbstractHeng, S., Moucheraud, C., Ochieng, E., Kweka, A., Wang, P., Xie, S., Ototo, J., Golub, G., Kapindo, E., Banda, E., Abdillahi, H., & others. (n.d.).Publication year
2025Journal title
VaccineVolume
55Page(s)
127025Abstract~Sensitivity analysis for binary outcome misclassification in randomization tests via integer programming
AbstractHeng, S., Heng, S., & Shaw, P. A. (n.d.).Publication year
2025Journal title
Journal of Computational and Graphical StatisticsVolume
34Issue
4Page(s)
1528--1541Abstract~A comprehensive graph pooling benchmark: Effectiveness, robustness and generalizability
AbstractHeng, S., Wang, P., Luo, J., Shen, Y., Zhang, M., Qin, S., Heng, S., & Luo, X. (n.d.).Publication year
2024Journal title
arXiv preprint arXiv:2406.09031Abstract~Adaptive Dwell Scheduling Based on Dual-Side Time Pointers for Simultaneous Multi-Beam Radar
AbstractHeng, S., Heng, S., Cheng, T., Song, J., He, Z., Liu, L., & Wang, Y. (n.d.).Publication year
2024Journal title
Tsinghua Science and TechnologyVolume
30Issue
3Page(s)
1190--1200Abstract~Bias reduction in matched observational studies with continuous treatments: Calipered non-bipartite matching and bias-corrected estimation and inference
AbstractHeng, S., Frazier, S. H., & Zhou, W. (n.d.).Publication year
2024Journal title
arXiv preprint arXivVolume
2409Abstract~Delta: Dual consistency delving with topological uncertainty for active graph domain adaptation
AbstractHeng, S., Wang, P., Cao, Y., Russell, C., Shen, Y., Luo, J., Zhang, M., Heng, S., & Luo, X. (n.d.).Publication year
2024Journal title
arXiv preprint arXiv:2409.08946Abstract~Generalized Rosenbaum bounds sensitivity analysis for matched observational studies with treatment doses: sufficiency, consistency, and efficiency
AbstractHeng, S., Heng, S., & Kang, H. (n.d.).Publication year
2024Journal title
arXiv e-printsPage(s)
arXiv--2403Abstract~Maximizing the reach of universal child sexual abuse prevention: Protocol for an equivalence trial
AbstractHeng, S., Guastaferro, K., Melchior, M. S., Heng, S., Trudeau, J., & Holloway, J. L. (n.d.).Publication year
2024Journal title
Contemporary clinical trials communicationsVolume
41Page(s)
101345Abstract~Re-evaluating the impact of reduced malaria prevalence on birthweight in sub-Saharan Africa: A pair-of-pairs study via two-stage bipartite and non-bipartite matching
AbstractHeng, S., Wang, P., Huang, P., Jin, Y., Shen, Y., Shahawy, O. E., Ham, D. W., O’Meara, W. P., & Heng, S. (n.d.).Publication year
2024Journal title
arXiv preprint arXiv:2409.19314Abstract~Real-time dwell scheduling based on a unified pulse interleaving framework for phased array radar
AbstractHeng, S., Cheng, T., Liu, L., Li, Z., & Heng, S. (n.d.).Publication year
2024Journal title
Tsinghua Science and TechnologyVolume
29Issue
5Page(s)
1540--1553Abstract~Sensitivity analysis for matched observational studies with continuous exposures and binary outcomes
AbstractHeng, S., Zhang, J., Small, D. S., & Heng, S. (n.d.).Publication year
2024Journal title
BiometrikaVolume
111Issue
4Page(s)
1349--1368Abstract~Towards Robust Matched Observational Studies with General Treatment Types: Consistency, Efficiency, and Adaptivity
AbstractHeng, S., Heng, S., Chiu, E. K., & Kang, H. (n.d.).Publication year
2024Journal title
arXiv preprint arXiv:2403.14152Abstract~