Olugbenga Ogedegbe

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Professor of Social and Behavioral Sciences

Professor for the Department of Population Health at NYU Grossman School of Medicine

Gbenga Ogedegbe, a physician, is Professor of Population Health & Medicine, Chief Division of Health & Behavior and Director Center for Healthful Behavior Change in the Department of Population Health at the School of Medicine. Gbenga is a leading expert on health disparities research; his work focuses on the implementation of evidence-based interventions for cardiovascular risk reduction in minority populations. He is Principal Investigator on numerous NIH projects, and has expanded his work globally to Sub-Saharan Africa where he is funded by the NIH to strengthen research capacity and reduce the burden of noncommunicable diseases. He has co-authored over 250 publications and his work has been recognized by receipt of several research and mentoring awards including the prestigious John M. Eisenberg Excellence in Mentorship Award from the Agency for Healthcare Research and Quality, and the Daniel Savage Science Award. He has served on numerous scientific panels including the NIH, CDC, World Health Organization, and the European Union Research Council. Prior to joining NYU, he was faculty at Cornell Weill Medical School and Columbia University College of Physicians and Surgeons.

Education

MPH from Columbia University, 1999

Residency, Montefiore Medical Center, Internal Medicine, 1998

MD from Donetsk University, 1988

Areas of research and study

Access to Healthcare

Global Health

Health of Marginalized Population

Implementation and Impact of Public Health Regulations

Implementation science

Stroke and Cardiovascular Disease

Publications

Hypertension in the high-cardiovascular-risk populations

McFarlane, S. I., Jean-Louis, G., Zizi, F., Whaley-Connell, A. T., Ogedegbe, O., Makaryus, A. N., & Maraj, I. (n.d.).

Publication year

2011

Journal title

International Journal of Hypertension

Volume

2011

10.4061/2011/746369

Management of hypertension among patients with coronary heart disease

Management of hypertension in high-risk ethnic minority with heart failure

Demede, M., Pandey, A., Innasimuthu, L., Jean-Louis, G., McFarlane, S. I., & Ogedegbe, G. (n.d.).

Publication year

2011

Journal title

International Journal of Hypertension

Volume

2011

10.4061/2011/417594

Abstract

Abstract

Hypertension (HTN) is the most common co-morbidity in the world, and its sequelae, heart failure (HF) is one of most common causes of mortality and morbidity in the world. Current understanding of pathophysiology and management of HTN in HF is mainly based on studies, which have mainly included whites. Among racial groups, African-American adults have the highest rates (44) of hypertension in the world and are more resistant to treatment. There is an emerging consensus on the significance of racial disparities in the pathophysiology and treatment options of hypertension and heart failure. However, African Americans had been underrepresented in all the trials until the initiation of the A-HEFT trial. Since the recognition of obstructive sleep apnea (OSA) as an important medical condition, large clinical trials have shown benefits of OSA treatment among patients with HTN and HF. This paper focuses on the pathophysiology, causes of secondary hypertension, and treatment of hypertension among African-American patients with heart failure. There is increasing need for randomized clinical trials testing innovative treatment options for African-American patients.

Meta-analysis: Impact of drug class on adherence to antihypertensives

Primary care equals secondary prevention in ischemic heart disease

Racial/ethnic residential segregation and self-reported hypertension among US-and Foreign-Born Blacks in New York City

Racism and hypertension: A review of the empirical evidence and implications for clinical practice

Resistant hypertension and obstructive sleep apnea in the primary-care setting

Resistant hypertension and sleep apnea: Pathophysiologic insights and strategic management

Williams, S. K., Ravenell, J., Jean-Louis, G., Zizi, F., Underberg, J. A., McFarlane, S. I., & Ogedegbe, G. (n.d.).

Publication year

2011

Journal title

Current Diabetes Reports

Volume

Issue

Page(s)

64-69

10.1007/s11892-010-0161-z

Abstract

Abstract

Resistant hypertension is common among adults with hypertension affecting up to 30% of patients. The treatment of resistant hypertension is important because suboptimal blood pressure control is the leading preventable cause of death worldwide. A frequent comorbid condition in patients with resistant hypertension is obstructive sleep apnea. The pathophysiology of sleep apnea-associated hypertension is characterized by sustained adrenergic activation and volume retention often posing treatment challenges in patients with resistant hypertension. This review will address some of the epidemiologic data associating apnea with the pathogenesis of resistant hypertension. Diagnosis and management of apnea and its associated hypertension will also be considered.

Socioeconomic position is positively associated with blood pressure dipping among African-American adults: The Jackson heart study

Technology-driven intervention to improve hypertension outcomes in community health centers

Shelley, D., Tseng, T. Y., Matthews, A. G., Wu, D., Ferrari, P., Cohen, A., Millery, M., Ogedegbe, O., Farrell, L., & Kopal, H. (n.d.).

Publication year

2011

Journal title

American Journal of Managed Care

Volume

Page(s)

SP103-SP110

Abstract

Abstract

Objectives: To assess the impact of an electronic medical record (EMR) with clinical decision support (CDS) and performance feedback on provider adherence to guideline-recommended care and blood pressure (BP) control compared with a standard EMR alone. Study Design: Quasi-experimental with repeated measures. Methods: The study was conducted in a 4-site, federally qualified health center, Open Door Family Medical Centers, located in New York. The research team, Open Door leadership, providers, and staff developed and implemented a tailored multicomponent CDS system, which included a BP alert, a hypertension (HTN) order set, an HTN template, and clinical reminders. We extracted patient-level data for each encounter 17 months prior to implementation of the intervention (June 2007-October 2008) and 15 months post-intervention (April 2009-June 2010), from the EMR's data tables for all adult nonobstetric patients with a diagnosis of HTN (N = 3636). Results: Rates of HTN control were significantly greater in the post-intervention period compared with the baseline period (50.9% vs 60.8%; P <.001). Process measures, derived from the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure Guidelines, also improved significantly. Logistic regression with generalized estimating equations showed that patients were 1.5 times more likely to have controlled BP post-intervention than pre-intervention. Correlates of poor BP control were black race, higher body mass index, diabetes, female gender, income, and a greater number of prescribed antihypertensive medications. Conclusions: Our findings suggest that health information technology that is implemented as part of a multicomponent quality improvement initiative can lead to improvements in HTN care and outcomes.

The counseling african americans to control hypertension (caatch) trial: Baseline demographic, clinical, psychosocial, and behavioral characteristics

Fernandez, S., Tobin, J. N., Cassells, A., Diaz-Gloster, M., Kalida, C., & Ogedegbe, G. (n.d.).

Publication year

2011

Journal title

Implementation Science

Volume

Issue

10.1186/1748-5908-6-100

Abstract

Abstract

Background: Effectiveness of combined physician and patient-level interventions for blood pressure (BP) control in low-income, hypertensive African Americans with multiple co-morbid conditions remains largely untested in community-based primary care practices. Demographic, clinical, psychosocial, and behavioral characteristics of participants in the Counseling African American to Control Hypertension (CAATCH) Trial are described. CAATCH evaluates the effectiveness of a multi-level, multi-component, evidence-based intervention compared with usual care (UC) in improving BP control among poorly controlled hypertensive African Americans who receive primary care in Community Health Centers (CHCs).Methods: Participants included 1,039 hypertensive African Americans receiving care in 30 CHCs in the New York Metropolitan area. Baseline data on participant demographic, clinical (e.g., BP, anti-hypertensive medications), psychosocial (e.g., depression, medication adherence, self-efficacy), and behavioral (e.g., exercise, diet) characteristics were gathered through direct observation, chart review, and interview.Results: The sample was primarily female (71.6%), middle-aged (mean age = 56.9 ± 12.1 years), high school educated (62.4%), low-income (72.4% reporting less than $20,000/year income), and received Medicaid (35.9%) or Medicare (12.6%). Mean systolic and diastolic BP were 150.7 ± 16.7 mm Hg and 91.0 ± 10.6 mm Hg, respectively. Participants were prescribed an average of 2.5 ± 1.9 antihypertensive medications; 54.8% were on a diuretic; 33.8% were on a beta blocker; 41.9% were on calcium channel blockers; 64.8% were on angiotensin converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs). One-quarter (25.6%) of the sample had resistant hypertension; one-half (55.7%) reported medication non-adherence. Most (79.7%) reported one or more co-morbid medical conditions. The majority of the patients had a Charlson Co-morbidity score ≥ 2. Diabetes mellitus was common (35.8%), and moderate/severe depression was present in 16% of participants. Participants were sedentary (835.3 ± 1,644.2 Kcal burned per week), obese (59.7%), and had poor global physical health, poor eating habits, high health literacy, and good overall mental health.Conclusions: A majority of patients in the CAATCH trial exhibited adverse lifestyle behaviors, and had significant medical and psychosocial barriers to adequate BP control. Trial outcomes will shed light on the effectiveness of evidence-based interventions for BP control when implemented in real-world medical settings that serve high numbers of low-income hypertensive African-Americans with multiple co-morbidity and significant barriers to behavior change.

Vitamin D and racial disparity in albuminuria: NHANES 2001-2006

Reflecting an increasing awareness of the importance of treatment adherence on outcomes in psychiatric populations, the National Institute of Mental Health (NIMH) convened a panel of treatment adherence researchers on September 27-28, 2007 to discuss and articulate potential solutions for dealing with methodological adherence research challenges. Panel discussions and presentations were augmented with targeted review of the literature on specific topics, with a focus on adherence to medication treatments in adults with serious mental illness. The group discussed three primary methodological areas: participants, measures, and interventions. When selecting patients for adherence-enhancing interventions (AEIs), a three-tier model was proposed that draws from the universal (targeting all patients receiving medication treatment for a specific condition, regardless of current adherence), selective (targeting patients at risk for nonadherence), and indicated (targeting patients who are currently nonadherent) prevention model and emphasizes careful patient characterization in relevant domains and appropriate matching of interventions to the selected population. Proposals were also made to reduce problematic selection biases in patient recruitment and retention. The panel addressed the pros and cons of various methods that can be used to measure adherence, and concluded that it is appropriate to use multiple measures whenever possible. Finally, the panel identified a broad range of intervention approaches, and conditions under which these interventions are likely to be most effective at reducing barriers to adherence and reinforcing adherence behavior.

New Recommendations for Treating Hypertension in Black Patients: Evidence and/or Consensus?

Wright, J. T., Agodoa, L. Y., Appel, L., Cushman, W. C., Taylor, A. L., Osei, K., Reed, J., & Ogedegbe, O. (n.d.).

Publication year

2010

Journal title

Hypertension

Volume

Issue

Page(s)

801-803

10.1161/HYPERTENSIONAHA.110.159566

Principles and Techniques of Blood Pressure Measurement

Ogedegbe, G., & Pickering, T. (n.d.).

Publication year

2010

Journal title

Cardiology Clinics

Volume

Issue

Page(s)

571-586

10.1016/j.ccl.2010.07.006

Abstract

Abstract

Although the mercury sphygmomanometer is widely regarded as the gold standard for office blood pressure measurement, the ban on use of mercury devices continues to diminish their role in office and hospital settings. To date, mercury devices have largely been phased out in United States hospitals. This situation has led to the proliferation of nonmercury devices and has changed (probably forever) the preferable modality of blood pressure measurement in clinic and hospital settings. In this article, the basic techniques of blood pressure measurement and the technical issues associated with measurements in clinical practice are discussed. The devices currently available for hospital and clinic measurements and their important sources of error are presented. Practical advice is given on how the different devices and measurement techniques should be used. Blood pressure measurements in different circumstances and in special populations such as infants, children, pregnant women, elderly persons, and obese subjects are discussed.

Sleep duration and the risk of diabetes mellitus: Epidemiologic evidence and pathophysiologic insights

Zizi, F., Jean-Louis, G., Brown, C. D., Ogedegbe, G., Boutin-Foster, C., & McFarlane, S. I. (n.d.).

Publication year

2010

Journal title

Current Diabetes Reports

Volume

Issue

Page(s)

43-47

10.1007/s11892-009-0082-x

Abstract

Abstract

Evidence from well-defined cohort studies has shown that short sleep, through sleep fragmentation caused by obstructive sleep apnea (OSA) or behavioral sleep curtailment because of lifestyle choices, is associated with increased incidence of diabetes. In this report, we review epidemiologic and clinical data suggesting that OSA is involved in the pathogenesis of altered glucose metabolism. Evidence suggesting increased risk of developing diabetes resulting from curtailed sleep duration is also considered. Proposed mechanisms explaining associations between short sleep and diabetes are examined and clinical management of OSA among patients with diabetes is discussed.

Olugbenga Ogedegbe