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Ralph DiClemente

Ralph DiClemente

Ralph DiClemente

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Professor of Social and Behavioral Sciences

Professional overview

Dr. Ralph DiClemente was trained as a Health Psychologist at the University of California, San Francisco where he received his PhD in 1984 after completing a ScM at the Harvard School of Public Health.  He earned his undergraduate degree at the City University of New York.

Dr. DiClemente’s research has four key foci:

  1. Developing interventions to reduce the risk of HIV/STD among vulnerable populations
  2. Developing interventions to enhance vaccine uptake among high-risk adolescents and women, such as HPV and influenza vaccine
  3. Developing implementation science interventions to enhance the uptake, adoption and sustainability of HIV/STD prevention programs in the community
  4. Developing diabetes screening and behavior change interventions to identify people with diabetes who are unaware of their disease status as well as reduce the risk of diabetes among vulnerable populations.

He has focused on developing intervention packages that blend community and technology-based approaches that are designed to optimize program effectiveness and enhance programmatic sustainability.

Dr. DiClemente is the author of ten CDC-defined, evidence-based interventions for adolescents and young African-American women and men. He is the author of more than 540 peer-review publications, 150 book chapters, and 21 books. He serves as a member of the Office of AIDS Research Advisory Council.

Previously, Dr. DiClemente served as the Charles Howard Candler Professor of Public Health at the Rollins School of Public Health at Emory University.  He was also Associate Director of the Center for AIDS Research, and was previously Chair of the Department of Behavioral Sciences and Health Education at the Rollins School of Public Health.

Dr. DiClemente is Past President of the Georgia chapter of the Society for Adolescent Health & Medicine.  He previously served as a member of the CDC Board of Scientific Counselors, and the NIMH Advisory Council.

Education

BA, The City College of the City University of New York (CCNY), New York, NY
ScM, Behavioral Sciences, Harvard University, Cambridge, MA
PhD, Health Psychology, University of California San Francisco Center for Behavioral Sciences, San Francisco, CA
Postdoctoral Fellow, University of California, San Francisco, CA

Areas of research and study

Community Interventions
Diabetes
HIV/AIDS
Implementation science
Influenza
Psychology

Publications

Publications

Rethinking funding priorities in mental health research

Lewis-Fernández, R., Rotheram-Borus, M. J., Betts, V. T., Greenman, L., Essock, M. S., Escobar, I. J., Barch, D., Hogan, M. F., Areán, P. A., Druss, B. G., DiClemente, R., McGlashan, T. H., Jeste, D. V., Proctor, E. K., Ruiz, P., John Rush, A., Canino, J. G., Bell, C. C., Henry, R., & Iversen, P. (n.d.).

Publication year

2016

Journal title

British Journal of Psychiatry

Volume

208

Issue

6

Page(s)

507-509
Abstract
Abstract
Mental health research funding priorities in high-income countries must balance longer-term investment in identifying neurobiological mechanisms of disease with shorter-term funding of novel prevention and treatment strategies to alleviate the current burden of mental illness. Prioritising one area of science over others risks reduced returns on the entire scientific portfolio.

Sexual Risk Among African American Women : Psychological Factors and the Mediating Role of Social Skills

Curran, T. M., Monahan, J. L., Samp, J. A., Coles, V. B., DiClemente, R., & Sales, J. (n.d.).

Publication year

2016

Journal title

Communication Quarterly

Volume

64

Issue

5

Page(s)

536-552
Abstract
Abstract
Prior research demonstrates a positive association between mental health problems and sexual risk for African American women. Using the social skills deficit hypothesis, we proposed that social skills mediate this relationship. African American women (n = 557, M age = 20.58) completed measures of depression, stress, emotional dysregulation, sexual risk behaviors, and perceptions of their social skills with their primary sexual partner. Social skills mediated the link between the mental health assessments and a composite sexual risk index. Theoretical implications of extending the social skill deficit hypothesis are discussed as well as implications for interventions.

Substance Use Patterns of HIV-Infected Russian Women with and Without Hepatitis C Virus Co-infection

Brown, J. L., DiClemente, R., Sales, J. M., Rose, E. S., Safonova, P., Levina, O. S., Belyakov, N., & Rassokhin, V. V. (n.d.).

Publication year

2016

Journal title

AIDS and Behavior

Volume

20

Issue

10

Page(s)

2398-2407
Abstract
Abstract
Individuals with HIV and hepatitis C virus (HCV) co-infection may experience substance use related health complications. This study characterized substance use patterns between HIV/HCV co-infected and HIV mono-infected Russian women. HIV-infected women (N = 247; M age = 30.0) in St. Petersburg, Russia, completed a survey assessing substance use, problematic substance use, and the co-occurrence of substance use and sexual behaviors. Covariate adjusted logistic and linear regression analyses indicated that HIV/HCV co-infected participants (57.1 %) reported more lifetime drug use (e.g., heroin: AOR: 13.2, 95 % CI 4.9, 35.3, p < .001), problem drinking (β = 1.2, p = .05), substance use problems (β = 1.3, p = .009), and increased likelihood of past injection drug use (AOR: 26.4, 95 % CI 8.5, 81.9, p < .001) relative to HIV mono-infected individuals. HIV/HCV co-infection was prevalent and associated with increased substance use and problematic drug use. Findings highlight the need for ongoing substance use and HIV/HCV risk behavior assessment and treatment among HIV/HCV co-infected Russian women.

Taking mhealth forward : Examining the core characteristics

Davis, T. L., DiClemente, R., & Prietula, M. (n.d.).

Publication year

2016

Journal title

JMIR mHealth and uHealth

Volume

4

Issue

3
Abstract
Abstract
The emergence of mobile health (mHealth) offers unique and varied opportunities to address some of the most difficult problems of health. Some of the most promising and active efforts of mHealth involve the engagement of mobile phone technology. As this technology has spread and as this technology is still evolving, we begin a conversation about the core characteristics of mHealth relevant to any mobile phone platform. We assert that the relevance of these characteristics to mHealth will endure as the technology advances, so an understanding of these characteristics is essential to the design, implementation, and adoption of mHealth-based solutions. The core characteristics we discuss are (1) the penetration or adoption into populations, (2) the availability and form of apps, (3) the availability and form of wireless broadband access to the Internet, and (4) the tethering of the device to individuals. These collectively act to both enable and constrain the provision of population health in general, as well as personalized and precision individual health in particular.

Validity of Self-reported Sexual Behavior Among Adolescents : Where Do We Go from Here?

DiClemente, R. (n.d.).

Publication year

2016

Journal title

AIDS and Behavior

Volume

20

Page(s)

215-217
Abstract
Abstract
Adolescents have high rates of sexually transmitted infections (STIs). Adolescents consuming alcohol and using drugs have markedly greater HIV/STI risk and are a priority population for intervention. Accurate measurement of sexual risk behavior is critical for understanding individual’s risk for HIV/STI, transmission dynamics of HIV/STI, and evaluating the efficacy of interventions designed reduce HIV/STI risk. However, significant challenges to accurately measuring adolescents’ self-reported sexual behavior are well-documented. Recent advances in microbiology, such as the use of less invasive specimen collection for DNA assays, can assist researchers in more accurately measuring adolescents’ sexual risk behavior. However, the majority of studies of adolescents’ sexual risk rely solely on self-reported behavior; therefore, methods to improve the validity of adolescents’ self-reported sexual behavior are needed. In addition, integrating biologic measures to complement self-reported measures are recommended, when appropriate and feasible.

Abuse Impedes Prevention : The Intersection of Intimate Partner Violence and HIV/STI Risk Among Young African American Women

Seth, P., Wingood, G. M., Robinson, L. S., Raiford, J. L., & DiClemente, R. (n.d.).

Publication year

2015

Journal title

AIDS and Behavior

Volume

19

Issue

8

Page(s)

1438-1445
Abstract
Abstract
Intimate partner violence (IPV) is associated with risky sexual behavior and STIs among diverse groups of women. IPV was examined as a moderator of efficacy for an HIV/STI intervention. 848 African American women, 18–29, were randomly assigned to an HIV/STI intervention or control condition. Participants completed measures on sociodemographics, IPV, risky sexual behavior and received STI testing. IPV predicted inconsistent condom use and a risky sexual partner over 12-month follow-up. A significant interaction indicated that among women who experienced IPV, those in the intervention were more likely to test positive for Trichomonas vaginalis (TV). Among intervention participants, those who experienced IPV were more likely to test TV-positive than those who did not. In an HIV intervention that did not specifically address IPV, women in the control condition were less likely to acquire TV than those in the intervention. Consideration of contextual/interpersonal factors is essential when developing HIV intervention programs.

Acceptance of and experiences utilising expedited partner therapy among African-American juvenile girls

Ricks, J. N., Swartzendruber, A. L., Sales, J. M., Boyce, L. S., DiClemente, R., & Rose, E. (n.d.).

Publication year

2015

Journal title

Sexual Health

Volume

12

Issue

4

Page(s)

364-368
Abstract
Abstract
Background The aim of this study was to describe acceptance of and experiences utilising expedited partner therapy (EPT) among African-American girls recruited from short-term juvenile detention centres. Methods: Ninety-five detained African-American girls (aged 13-17 years) completed audio computer-assisted self-interviews (ACASI) and self-collected vaginal swab specimens assayed for chlamydia and gonorrhoea. EPT was offered to sexually transmissible infection (STI)-positive participants (n≤51); follow-up phone interviews assessed medication delivery to partners. Summary statistics described EPT acceptance frequency. Generalised estimating equations assessed correlates of acceptance. Nine semi-structured interviews elicited EPT experiences. Results: EPT was offered 69 times, accepted by 70% (n≤37) girls and provided to 68% (n≤36) of girls. Acceptance was significantly associated with sexual risk behaviours such as infrequent partner STI prevention discussion (OR≤3.2, 95% CI: 1.0,-10.1, P≤0.048) and≥4 lifetime sex partners (OR≤3.3, 95% CI: 1.0-11.0, P≤0.048). Discontinued relationships were the most common barrier to EPT acceptance. Emergent interview themes included sense of responsibility, which appeared to motivate acceptance and help overcome identified discomfort with partner disclosure conversations. Conclusions: Future research is needed to determine EPT efficacy among African-American juvenile populations and feasibility of its use outside of research settings.

Association of depressive symptoms and substance use with risky sexual behavior and sexually transmitted infections among African American female adolescents seeking sexual health care

Jackson, J. M., Seth, P., DiClemente, R., & Lin, A. (n.d.).

Publication year

2015

Journal title

American journal of public health

Volume

105

Issue

10

Page(s)

2137-2142
Abstract
Abstract
Objectives. We examined how depression and substance use interacted to predict risky sexual behavior and sexually transmitted infections (STIs) among African American female adolescents. Methods. We measured depressive symptoms, substance use, sexual behavior, and STIs in 701 African American female adolescents, aged 14 to 20 years, at baseline and at 6-month intervals for 36 months in Atlanta, Georgia (2005?2007). We used generalized estimating equation models to examine effects over the 36-month follow-up period. Results. At baseline, more than 40% of adolescents reported significant depressive symptoms; 64% also reported substance use in the 90 days before assessment. Depression was associated with recently incarcerated partner involvement, sexual sensation seeking, unprotected sex, and prevalent STIs (all P < .001). In addition, adolescents with depressive symptoms who reported any substance use (i.e., marijuana, alcohol, Ecstasy) were more likely to report incarcerated partner involvement, sexual sensation seeking, unprotected sex, and have an incident STI over the 36-month follow-up (all P < .05). Conclusions. African American female adolescents who reported depressive symptoms and substance use weremore likely to engage in risky behavior and acquire incident STIs. This populationmight benefit from future prevention efforts targeting the intersection of depression and substance use.

Associations Between a Dopamine D4 Receptor Gene, Alcohol Use, and Sexual Behaviors Among Female Adolescent African Americans

Sales, J. M., Smearman, E. L., Brown, J. L., Brody, G. H., Philibert, R. A., Rose, E., & DiClemente, R. (n.d.).

Publication year

2015

Journal title

Journal of HIV/AIDS and Social Services

Volume

14

Issue

2

Page(s)

136-153
Abstract
Abstract
Young female adolescent African Americans are disproportionately impacted by HIV infection. There is a clear need to understand factors associated with increased HIV-risk behaviors among this vulnerable population. We sought to explore the association between a dopamine D4 receptor gene (DRD4), a genetic marker associated with natural variations in rewarding behaviors, and self-reported alcohol use and sexual risk behaviors, while controlling for other known correlates of risk-taking such as impulsivity, sensation-seeking, and peer norms, among a group of high-risk female adolescent African Americans to evaluate whether this biological factor enhances understanding of the patterns of risk in this vulnerable group.

Erratum to : Neighborhood Condition and Geographic Locale in Assessing HIV/STI Risk Among African American Adolescents [AIDS and Behavior, DOI:10.1007/s10461-014-0868-y]

Kerr, J. C., Valois, R. F., Siddiqi, A., Vanable, P., Carey, M. P., DiClemente, R., Romer, D., Brown, L. K., Farber, N. B., & Salazar, L. F. (n.d.).

Publication year

2015

Journal title

AIDS and Behavior

Volume

19

Issue

6

Page(s)

1014-1015
Abstract
Abstract
~

Explaining racial disparities in HIV incidence in black and white men who have sex with men in Atlanta, GA : A prospective observational cohort study

Sullivan, P. S., Rosenberg, E. S., Sanchez, T. H., Kelley, C. F., Luisi, N., Cooper, H. L., DiClemente, R., Wingood, G. M., Frew, P. M., Salazar, L. F., del Rio, C., Mulligan, M. J., & Peterson, J. L. (n.d.).

Publication year

2015

Journal title

Annals of Epidemiology

Volume

25

Issue

6

Page(s)

445-454
Abstract
Abstract
Purpose: To describe factors associated with racial disparities in HIV (human immunodeficiency virus) incidence among men who have sex with men (MSM) in the United States. Methods: In a longitudinal cohort of black and white HIV-negative MSM in Atlanta, HIV incidence rates were compared by race. Incidence hazard ratios (HRs) between black and white MSM were estimated with an age-scaled Cox proportional hazards model. A change-in-estimate approach was used to understand mediating time-independent and -dependent factors that accounted for the elevated HR. Results: Thirty-two incident HIV infections occurred among 260 black and 302 white MSM during 843 person-years (PY) of follow-up. HIV incidence was higher among black MSM (6.5/100 PY; 95% confidence interval [CI]: 4.2-9.7) than white MSM (1.7/100 PY; CI: 0.7-3.3) and highest among young (18-24years) black MSM (10.9/100 PY; CI: 6.2-17.6). The unadjusted hazard of HIV infection for black MSM was 2.9 (CI: 1.3-6.4) times that of white MSM; adjustment for health insurance status and partner race explained effectively all of the racial disparity. Conclusions: Relative to white MSM in Atlanta, black MSM, particularly young black MSM, experienced higher HIV incidence that was not attributable to individual risk behaviors. In a setting where partner pool risk is a driver of disparities, it is also important to maximize care and treatment for HIV-positive MSM.

Focusing national institutes of health HIV/AIDS research for maximum population impact

Walensky, R. P., Carpenter, C. J., Auerbach, J. D., Agosto-Rosario, M., Averitt, D., Bartlett, J. G., Curran, J. W., DiClemente, R., El-Sadr, W., Haase, A., Hillier, S., Holmes, K. K., & Volberding, P. A. (n.d.).

Publication year

2015

Journal title

Clinical Infectious Diseases

Volume

60

Issue

6

Page(s)

937-940
Abstract
Abstract
Progress in advancing research on the pathophysiology, prevention, treatment, and impact of human immunodeficiency virus (HIV) is threatened by the decaying purchasing power of National Institutes of Health (NIH) dollars. A working group of the NIH Office of AIDS Research Advisory Council was charged by the NIH Director with developing a focused and concise blueprint to guide the use of limited funding over the next few years. Science priorities outlined by the working group and reported here are intended to maximally address individuals, groups, and settings most affected by the epidemic, and to redress shortcomings in realizing population- level HIV prevention, treatment, and eradication goals. Optimizing these priorities requires that traditional silos-defined by topic focus and by scientific discipline-be dissolved and that structural issues affecting the pipeline of new investigators and the ability of the Office of AIDS Research to fulfill its role of steward of the NIH HIV/AIDS research program be directly addressed.

Genetic sensitivity to emotional cues, racial discrimination and depressive symptoms among African–American adolescent females

Sales, J. M., Brown, J. L., Swartzendruber, A. L., Smearman, E. L., Brody, G. H., & DiClemente, R. (n.d.).

Publication year

2015

Journal title

Frontiers in Psychology

Volume

6
Abstract
Abstract
Psychosocial stress, including stress resulting from racial discrimination (RD), has been associated with elevated depressive symptoms. However, individuals vary in their reactivity to stress, with some variability resulting from genetic differences. Specifically, genetic variation within the linked promoter region of the serotonin transporter gene (5-HTTLPR) is related to heightened reactivity to emotional environmental cues. Likewise, variations within this region may interact with stressful life events (e.g., discrimination) to influence depressive symptoms, but this has not been empirically examined in prior studies. The objective of this study was to examine whether variation in the 5-HTTLPR gene interacts with RD to predict depressive symptoms among a sample of African–American adolescent females. Participants were 304 African–American adolescent females enrolled in a sexually transmitted disease prevention trial. Participants completed a baseline survey assessing psychosocial factors including RD (low vs. high) and depressive symptomatology (low vs. high) and provided a saliva sample for genotyping the risk polymorphism 5-HTTLPR (s allele present vs. not present). In a logistic regression model adjusting for psychosocial correlates of depressive symptoms, an interaction between RD and 5-HTTLPR group was significantly associated with depressive symptomatology (AOR = 3.79, 95% CI: 1.20–11.98, p = 0.02). Follow-up tests found that high RD was significantly associated with greater odds of high depressive symptoms only for participants with the s allele. RD and 5-HTTLPR status interact to differentially impact depressive symptoms among African–American adolescent females. Efforts to decrease depression among minority youth should include interventions which address RD and strengthen factors (e.g., coping, emotion regulation, building support systems) which protect youth from the psychological costs of discrimination.

Human papillomavirus vaccination among adolescents in Georgia

Underwood, N. L., Weiss, P., Gargano, L. M., Seib, K., Rask, K. J., Morfaw, C., Murray, D., DiClemente, R., Hughes, J. M., & Sales, J. M. (n.d.).

Publication year

2015

Journal title

Human Vaccines and Immunotherapeutics

Volume

11

Issue

7

Page(s)

1703-1708
Abstract
Abstract
Human papillomavirus (HPV) vaccination coverage for adolescent females and males remains low in the United States. We conducted a 3-arm randomized controlled trial (RCT) conducted in middle and high schools in eastern Georgia from 2011–2013 to determine the effect of 2 educational interventions used to increase adolescent vaccination coverage for the 4 recommended adolescent vaccines: Tdap, MCV4, HPV and influenza. As part of this RCT, this article focuses on: 1) describing initiation and completion of HPV vaccine series among a diverse population of male and female adolescents; 2) assessing parental attitudes toward HPV vaccine; and 3) examining correlates of HPV vaccine series initiation and completion. Parental attitude score was the strongest predictor of HPV vaccine initiation among adolescents (adjusted odds ratio (aOR): 2.08; 95% confidence interval (CI): 1.80, 2.39). Other correlates that significantly predicted HPV series initiation were gender, study year, and intervention arm. Parental attitudes remained a significant predictor of receipt of 3 doses of HPV vaccine along with gender, race, school type and insurance type. This study demonstrates that positive parental attitudes are important predictors of HPV vaccination and critical to increasing coverage rates. Our findings suggest that more research is needed to understand how parental attitudes are developed and evolve over time.

Identifying psychosocial and social correlates of sexually transmitted diseases among black female teenagers

Kraft, J. M., Whiteman, M. K., Carter, M. W., Snead, M. C., DiClemente, R., Murray, C. C., Hatfield-Timajchy, K., & Kottke, M. (n.d.).

Publication year

2015

Journal title

Sexually Transmitted Diseases

Volume

42

Issue

4

Page(s)

192-197
Abstract
Abstract
Background: Black teenagers have relatively high rates of sexually transmitted diseases (STDs), and recent research suggests the role of contextual factors, as well as risk behaviors.We explore the role of 4 categories of risk and protective factors on having a biologically confirmed STD among black, female teenagers. Methods: Black teenage girls (14-19 years old) accessing services at a publicly funded family planning clinic provided a urine specimen for STD testing and completed an audio computer-assisted self-interview that assessed the following: risk behaviors, relationship characteristics, social factors, and psychosocial factors. We examined bivariate associations between each risk and protective factor and having gonorrhea and/or chlamydia, as well as multivariate logistic regression among 339 black female teenagers. Results: More than one-fourth (26.5%) of participants had either gonorrhea and/or chlamydia. In multivariate analyses, having initiated sex before age 15 (adjusted odds ratio [aOR], 1.87) and having concurrent sex partners in the past 6 months (aOR, 1.55) were positively associated with having an STD. Living with her father (aOR, 0.44), believing that an STD is theworst thing that could happen (aOR, 0.50), and believing shewould feel dirty and embarrassed about an STD (aOR, 0.44) were negatively associated with having an STD. Conclusions: Social factors and attitudes toward STDs and select risk behaviors were associated with the risk for STDs, suggesting the need for interventions that address more distal factors. Future studies should investigate how such factors influence safer sexual behaviors and the risk for STDs among black female teenagers.

Influence of sexual arousability on partner communication mediators of condom use among African American female adolescents

Swartzendurber, A., Murray, S. H., Sales, J. M., Milhausen, R. R., Sanders, S. A., Graham, C. A., DiClemente, R., & Wingood, G. M. (n.d.).

Publication year

2015

Journal title

Sexual Health

Volume

12

Issue

4

Page(s)

322-327
Abstract
Abstract
Background Ample evidence shows that partner sexual communication is related to condom use. Although communication about safer sex may often occur when sexual arousal is high, no studies have examined arousability, one's propensity for sexual arousal and partner sexual communication. The purpose of this study was to examine associations between sexual arousability and partner-related mediators of condom use among African American female adolescents, who have disproportionate risk for HIV and sexually transmissible infections (STIs). Methods: The study analysed self-reported baseline data from 701 African American females aged 14-20 years participating in a HIV/STI trial. Linear regression models examined associations between arousability and partner-related mediators of condom use (partner sexual communication self-efficacy, partner sexual communication frequency, sex refusal self-efficacy and condom use self-efficacy), controlling for age, impulsivity and relationship power. Results: Greater arousability was significantly associated with reduced levels of each partner communication outcome assessed (partner sexual communication self-efficacy, partner sexual communication frequency and sex refusal self-efficacy) but was not associated with condom use self-efficacy. Conclusions: Arousal and other positive aspects of sex have largely been ignored by HIV/STI prevention efforts, which primarily focus on individual behaviour. A population-level sexual health approach focusing on sexual wellbeing may reduce stigma, facilitate partner sexual communication and be more effective at reducing HIV/STI rates than traditional approaches.

Influence of sources of information about influenza vaccine on parental attitudes and adolescent vaccine receipt

Gargano, L. M., Underwood, N. L., Sales, J. M., Seib, K., Morfaw, C., Murray, D., DiClemente, R., & Hughes, J. M. (n.d.).

Publication year

2015

Journal title

Human Vaccines and Immunotherapeutics

Volume

11

Issue

7

Page(s)

1641-1647
Abstract
Abstract
In 2011–2012, only 34% of 13–17 years olds in the United States (US) received seasonal influenza vaccine. Little is known about the link between parents' sources of health information, their vaccine-related attitudes, and vaccination of their adolescent against influenza. This study seeks to determine the relationship between number of sources of information on influenza vaccine, parental attitudes toward influenza vaccine, and influenza vaccine uptake in adolescents. We conducted a telephone and web-based survey among US parents of students enrolled in 6 middle and 5 high schools in Georgia. Bivariate and multivariable analyses were conducted to examine associations between the number of information sources about influenza vaccine and vaccine receipt and whether parent vaccine-related attitudes act as a mediator. The most commonly reported sources of information were: a physician/medical professional (95.0%), a family member or friend (80.6%), and television (77.2%). Parents who had higher attitude scores toward influenza vaccine were 5 times as likely to report their adolescent had ever received influenza vaccine compared to parents who had lower attitude scores (adjusted odds ratio (aOR) 5.1; 95% confidence intervals (CI) 3.1–8.4; P < 0.01). Parent vaccine-related attitudes were a significant mediator of the relationship between sources of information and vaccine receipt. In light of the low response rate and participation in an adolescent vaccination intervention, findings may not be generalizable to other populations. This study shows the importance of multiple sources of information in influencing parental decision-making about influenza vaccine for adolescents. Harnessing the power of mass media and family members and friends as health advocates for influenza vaccination can potentially help increase vaccination coverage of adolescents.

Overcoming barriers to HPV vaccination : A randomized clinical trial of a culturally-tailored, media intervention among African American girls

DiClemente, R., Murray, C. C., Graham, T., & Still, J. (n.d.).

Publication year

2015

Journal title

Human Vaccines and Immunotherapeutics

Volume

11

Issue

12

Page(s)

2883-2894
Abstract
Abstract
Although genital HPV is the most prevalent STI in the US, rates of vaccination uptake among high-risk subgroups remain low. Investigations of vaccine compliance have mainly targeted mother-daughter dyads, which in some settings may prove difficult. This study examines an innovative culturally tailored, computer-delivered media-based strategy to promote HPV vaccine uptake. Data, inclusive of sociodemographics, sexual behaviors, knowledge, attitudes, and beliefs about HPV and vaccination were collected via ACASI from 216 African American adolescent females (ages 14-18 years) seeking services in family planning and STI public health clinics in metropolitan Atlanta. Data were obtained prior to randomization and participation in an interactive media-based intervention designed to increase HPV vaccination uptake. Medical record abstraction was conducted 7 month post-randomization to assess initial vaccine uptake and compliance. Participants in the intervention were more compliant to vaccination relative to a placebo comparison condition (26 doses vs. Seventeen doses; p=0.12). However, vaccination series initiation and completion were lower than the national average. Thorough evaluation is needed to better understand factors facilitating HPV vaccine uptake and compliance, particularly perceived susceptibility and the influence of the patient-provider encounter in a clinical setting.

Perceived Difficulty of Performing Selected HIV/AIDS Preventive Behaviors and Life Satisfaction : Is there a Relationship for African American Adolescents?

Valois, R. F., Kerr, J. C., Hennessy, M., DiClemente, R., Brown, L. K., Carey, M. P., Vanable, P. A., Farber, N. B., Salazar, L. F., & Romer, D. (n.d.).

Publication year

2015

Journal title

AIDS and Behavior

Volume

19

Issue

7

Page(s)

1288-1297
Abstract
Abstract
Research on the relationship between adolescent health risk behaviors, sexual risk behaviors in particular, and perceived life satisfaction is emerging. Some researchers suggest that life satisfaction has been a neglected component of adolescent health research. African American adolescents aged 13–18 (n = 1,658) from four matched, mid-sized cities in the northeastern and southeastern USA, completed a self-report questionnaire via Audio Computer Assisted Self-Interview. Analyses were conducted to examine relationships between perceived difficulty in performing HIV/AIDS preventive behavior and perceived life satisfaction, while controlling for socioeconomic status. Results suggest that perceived life satisfaction is related to perceived difficulty in performing HIV/AIDS preventive behaviors, for both males and females, with variability in the magnitude of associations by gender. Further research is necessary to identify the particular characteristics of youth and specific aspects of adolescent life satisfaction associated with perceived difficulty in performing HIV/AIDS preventive behavior to develop gender-appropriate and culturally-sensitive quality of life/health promotion programs.

School-located vaccination clinics for adolescents : Correlates of acceptance among parents

Gargano, L. M., Weiss, P., Underwood, N. L., Seib, K., Sales, J. M., Vogt, T. M., Rask, K., Morfaw, C., Murray, D. L., DiClemente, R., & Hughes, J. M. (n.d.).

Publication year

2015

Journal title

Journal of Community Health

Volume

40

Issue

4

Page(s)

660-669
Abstract
Abstract
Four vaccines are recommended by The Advisory Committee for Immunization Practices for adolescents: tetanus, diphtheria, acellular pertussis vaccine (Tdap), meningococcal conjugate vaccine (MCV4), human papillomavirus vaccine (HPV), and annual seasonal influenza vaccine. However, coverage among adolescents is suboptimal. School-located vaccination clinics (SLVCs) offer vaccines to students at school, increasing access. This study seeks to determine the relationship between attitudes of parents of middle- and high-school students and acceptance of SLVCs for all four adolescent recommended vaccines. We conducted a telephone and web-based survey among parents of students enrolled in six middle and five high schools in Georgia. Analyses were conducted to examine associations between parental attitudes and willingness to allow their child to be vaccinated at school. Tdap and influenza vaccine had the highest rates of parental SLVC acceptance while HPV vaccine had the lowest. Parents who accepted SLVCs had higher perceived severity of influenza, meningococcal, and HPV illnesses compared to parents who did not accept SLVC. Intention to vaccinate was associated with SLVC acceptance for Tdap [Adjusted OR (AOR) 7.38; 95 % confidence interval (CI) 2.44-22.31], MCV4 (AOR 2.97; 95 % CI 1.67-5.28), and HPV vaccines (AOR 7.61; 95 % CI 3.43-16.89). Social norms were associated with acceptance of SLVCs for influenza vaccine (AOR 1.44; 95 % CI 1.12-1.84). These findings suggest parents of adolescents are generally supportive of SLVCs for recommended adolescent vaccines. Perceived severity of illness and intention to get their adolescent vaccinated were the most consistent correlates of parental SLVC acceptance for all vaccines. Future SLVC planning should focus on perceptions of disease severity and benefits of vaccination.

The association between stress, coping, and sexual risk behaviors over 24 months among African-American female adolescents

Hulland, E. N., Brown, J. L., Swartzendruber, A. L., Sales, J. M., Rose, E. S., & DiClemente, R. (n.d.).

Publication year

2015

Journal title

Psychology, Health and Medicine

Volume

20

Issue

4

Page(s)

443-456
Abstract
Abstract
Heightened psychosocial stress coupled with maladaptive coping may be associated with greater sexual risk engagement. This study examined the association between stress levels and coping strategy use as predictors of sexual risk behavior engagement over 24 months among African-American adolescent females (N = 701; M = 17.6 years) enrolled in an STI/HIV risk-reduction intervention program. Participants completed audio computer assisted self-interview (ACASI) measures of global stress, interpersonal stress, coping strategy use, and sexual behaviors prior to intervention participation. Follow-up ACASI assessments were conducted at 6, 12, 18, and 24 months post-intervention. Generalized estimated equation models examined associations between baseline stress levels and coping strategy use as predictors of condom use (past 90 days, last sex) and multiple partners during follow-up. Global stress and individual coping strategy usage were not associated with differences in condom use. Higher interpersonal stress was associated with lower proportion condom use (p =.018), inconsistent condom use (p =.011), and not using a condom at last sex (p =.002). There were no significant associations between stress levels, coping strategy use, and multiple partners. Future research should explore mechanisms that may underlie the association between elevated interpersonal stress and decreased condom use among this population.

The effect of high rates of bacterial sexually transmitted infections on hiv incidence in a cohort of black and white men who have sex with men in Atlanta, Georgia

Kelley, C. F., Vaughan, A. S., Luisi, N., Sanchez, T. H., Salazar, L. F., Frew, P. M., Cooper, H. L., DiClemente, R., Del Rio, C., Sullivan, P. S., & Rosenberg, E. S. (n.d.).

Publication year

2015

Journal title

AIDS Research and Human Retroviruses

Volume

31

Issue

6

Page(s)

587-592
Abstract
Abstract
Data reporting sexually transmitted infection (STI) incidence rates among HIV-negative U.S. men who have sex with men (MSM) are lacking. In addition, it is difficult to analyze the effect of STI on HIV acquisition given that sexual risk behaviors confound the relationship between bacterial STIs and incident HIV. The InvolveMENt study was a longitudinal cohort of black and white HIV-negative, sexually active MSM in Atlanta who underwent routine screening for STI and HIV and completed behavioral questionnaires. Age-adjusted incidence rates were calculated for urethral and rectal Chlamydia (CT), gonorrhea (GC), and syphilis, stratified by race. Propensity-score-weighted Cox proportional hazards models were used to estimate the effect of STI on HIV incidence and calculate the population attributable fraction (PAF) for STI. We included 562 HIV-negative MSM with 843 person-years of follow-up in this analysis. High incidence rates were documented for all STIs, particularly among black MSM. Having a rectal STI was significantly associated with subsequent HIV incidence in adjusted analyses (aHR 2.7; 95% CI 1.2, 6.4) that controlled for behavioral risk factors associated with STI and HIV using propensity score weights. The PAF for rectal STI was 14.6 (95% CI 6.8, 31.4). The high incidence of STIs among Atlanta MSM and the association of rectal STI with HIV acquisition after controlling for behavioral risk underscore the importance of routine screening and treatment for STIs among sexually active MSM. Our data support targeting intensive HIV prevention interventions, such as preexposure chemoprophylaxis (PrEP), for Atlanta MSM diagnosed with rectal STIs.

The effects of a mass media HIV-risk reduction strategy on HIV-related stigma and knowledge among African American adolescents

Kerr, J. C., Valois, R. F., DiClemente, R., Carey, M. P., Stanton, B., Romer, D., Fletcher, F., Farber, N., Brown, L. K., Vanable, P. A., Salazar, L. F., Juzang, I., & Fortune, T. (n.d.).

Publication year

2015

Journal title

AIDS patient care and STDs

Volume

29

Issue

3

Page(s)

150-156
Abstract
Abstract
HIV-related stigma undermines HIV prevention, testing, and treatment. Multipronged risk-reduction strategies may reduce stigma among African American adolescents. To test the effectiveness of a risk-reduction strategy in addressing stigma, 1613 African American adolescents from four mid-sized cities participated in a randomized control trial. Participants received a sexual-risk reduction [Focus on Youth (FOY)] or general health curriculum [Promoting Health Among Teens (PHAT)]. Two cities received a culturally-tailored media intervention. Participants completed baseline, 3-, 6-, and 12-month surveys to measure HIV-related stigma and knowledge. Analysis of covariance tested for stigma and knowledge differences by media city status and curriculum/media city status (PHAT media vs. PHAT non-media, FOY media vs. FOY non-media; FOY media vs. PHAT media; FOY non-media vs. PHAT non-media) at each measurement. Hierarchical linear modeling (HLM) determined stigma and knowledge differences over time. Media participants demonstrated greater HIV-related knowledge (p

The moderating role of parental psychopathology on response to a family-based HIV prevention intervention among youth in psychiatric treatment

DiClemente, R. (n.d.).

Publication year

2015

Journal title

Journal of Family Studies

Volume

21

Issue

2

Page(s)

178-194
Abstract
Abstract
Previous research suggests parents with mental health concerns are more likely to engage in maladaptive parenting practices and are less likely to benefit from parenting interventions. The current study examined the moderating influence of parent mental health problems on response to a family HIV prevention program delivered to youth in mental health treatment and their caregivers. The family intervention targeted parentadolescent communication and parental monitoring. Study hypotheses were tested using general linear models at three- and six-month follow-ups. Tests of moderation were conducted by modeling the interaction between treatment condition (family versus control) and parental psychopathology controlling for other relevant psychosocial factors (i.e., single parenthood, income, and education). Parents with elevated psychiatric symptoms demonstrated greater improvements in sexual communication (three and six months) and parental monitoring (three months) following the familybased intervention. These results suggest that parents with mental health problems can benefit from a brief family HIV prevention program.

The need for biological outcomes to complement self-report in adolescent research

Brown, J. L., & DiClemente, R. (n.d.).

Publication year

2015

Journal title

Pediatrics

Volume

136

Issue

3

Page(s)

e551-e553
Abstract
Abstract
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Contact

rjd438@nyu.edu 708 Broadway New York, NY, 10003